Intermittent claudication and endothelial dysfunction
نویسندگان
چکیده
منابع مشابه
Selective cyclooxygenase-2 inhibition reduces endothelial dysfunction and improves inflammatory status in patients with intermittent claudication.
INTRODUCTION AND OBJECTIVES Both endothelial dysfunction and a proinflammatory state are present during the early stages of atherosclerosis. In this context, increased expression of cyclooxygenase-2 (COX-2) results in higher levels of vasoconstrictive and proinflammatory substances. The aim of this study was to investigate the influence of COX-2 activity on endothelial dysfunction associated wi...
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O15 ENDOTHELIAL DYSFUNCTION IN INTERMITTENT CLAUDICATION R Sarvanandan, RA Lane, IC Chetter Academic Vascular Unit, Hull Royal Infirmary/Hull York Medical School Introduction Endothelial dysfunction is integral to the development of atherosclerosis and subsequent plaque progression. In coronary disease, there is an association between disease severity and arterial stiffness and endothelial dysf...
متن کاملIntermittent claudication
Peripheral arterial disease is a common health problem that globally affects over 200 million individuals, and intermittent claudication (IC) is the most common symptomatic presentation. The leg symptoms in IC are provoked by walking exercise and can be alleviated by medical intervention, exercise training and invasive vascular interventions (revascularization). The quality of evidence for inva...
متن کاملExercise and Intermittent Claudication
Four men with arteriosclerosis obliterans (ASO) were exercised on a treadmill on 4 different days to determine their maximal walking time (MWT) and the point at which their claudication pain (CPT) began. Each subject was exercised at 60%, 75%, and 90% of his MWT to determine the effect of work intensity on the systolic blood pressure at the ankle (AP). To measure the effect of exercise repeated...
متن کاملExercise and Intermittent Claudication
Nineteen patients with obliterative arteriosclerotic disease of the legs and suffering from intermittent claudication were studied before and during a 6 months' training program. The maximal walking distance and the calf muscle blood flow during walking (xenon-133 clearance technique) was recorded at monthly intervals. A significant correlation was established between improvement in maximal wal...
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ژورنال
عنوان ژورنال: European Heart Journal Supplements
سال: 2002
ISSN: 1520-765X
DOI: 10.1016/s1520-765x(02)90015-5